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1st joint conference SMMAP 2017

Françoise Immel and Laetitia Fouillen came back from Disneyland Paris where they attended the 1st joint conference SMMAP 2017 : Mass Spectrometry, Metabolomics and Proteomic Analysis 2017

This unique event, which will host more than 450 participants, will foster interdisciplinarity, as well as scientific exchanges between communities that traditionally meet separately. It will also be an opportuniy to broaden our knowledge, share experiences and create new links, both scientific and personal. The conference will also welcome scientists from the private sector, working on instrumentation, sample preparation and data processing.


Eric Testet, in collaboration with Pascale de Lonlay et al., has published in Journal of Lipid Research. In this paper, they showed a normal human adipose tissue functions and differentiation in patients with LIPIN1 mutations. Especially, they analyzed the qualitative composition of the storage lipids in white adipose tissue.
Normal human adipose tissue functions and differentiation in patients
with biallelic LPIN1 inactivating mutations


William Nicolas, Magali Grison and Emmanuelle Bayer exposed their view on the origin of plasmodesmata and other membranous pores, and how plasmodesmata can now be viewed as highly specialised membrane contact sites. Lipid composition and membrane mechanics have a tremendous impact on plasmodesmal structure and functionality, in terms of cell-to-cell connectivity modulation (size exclusion limit) but also in terms of lateral inter-compartment exchanges (endoplasmic reticulum to plasma membrane). This work was published inJExBot.


William Nicolas and colleagues show a novel type of plasmodesmata that they labeled type I plasmodesmata. These pores are characterized by a very tight desmotubule-plasma membrane proximity leaving very little space for cytoplasmic sleeve. They are preferentially associated to post-cytokinesis division thin division walls. FRAP and photoactivation experiments in parallel unexpectedly revealed that these pores can actually convey molecular transport of macromolecules up to GFP (28kDa), thus forcing a reconsideration of the classic model where size exclusion limit is a function of the cytoplasmic sleeve width. This work was published in Nature Plants