[May 9, 2012] Dr Pascale de Lonlay from the Hôpital Necker-enfants malades in Paris gave in the lab this morning a very interesting talk on the autosomal recessive LPIN1 mutations recently described as a novel cause of rhabdomyolysis in few families. This protein is likely links with disorder of the lipid metabolism. Dr de Lonlay was invited by Eric Testet to discuss a collaboration with the LBM and the lipidomic platform.

[May 9, 2012] Ian Pulsifer from Pr O. Rowland’s lab at Carleton University (Ottawa, Canada) is visiting us for 10 days. He is supported by a FCRF grant (France Canada Research Fund) obtained by F. Domergue and O. Rowland. Ian will express Arabidopsis proteins in E. coli and characterize the compounds resulting from their expression by GC-MS. Have fun in Bordeaux!!


[May 7, 2012] "Lipids of plant membrane rafts". This is the title of our recent invited review published in Progress in Lipid Research (http://dx.doi.org/10.1016/j.plipres.2012.04.001). As stated, this article wrote conjointly by members of the "Biomembranes and Membrane Lipids" reviews the current knowledge and perspectives on phospholipids, sphingolipids and phytosterols in plant raft microdomains going from model membranes to vizualisation and cellular functions.


ANOUNCEMENT: After the successful "Patchy Prague 2010", comes now "Dijon Domains 2012" https://colloque.inra.fr/dijon_domains
This conference, which will be held in Dijon from 27 to 30 November 2012,  will be dedicated to the most advanced methodologies allowing the study of membrane sub-compartmentation, the latest exciting discoveries concerning the characterization of membrane organization, and the most recent evidences indicating a crucial role of this organization and its dynamics in signaling processes and cell physiology.
Very famous speakers accepted the invitation in Dijon like Kai Simons, Erwin London, Luis Bagatolli, Katharina Gaus, Didier Marguet, Bridget Wilson, Tobias Walther and will give plenary invited lectures

[April 18, 2012] We were glad to hear the talk of Federica Brandizzi from Michigan State University, USA (http://www.prl.msu.edu/Facultypages/Brandizzi.html) on news and views in the activities of the plant Endoplasmic Reticulum. Federica whose is a close collaborator of Patrick Moreau from the LBM, was invited by our lab and the SFR "Biologie Intégrative et Ecologie".
Thank you Fede', for the visit, see you soon.


[Avril 18, 2012]  The project « MetaboHub » which aims to coordinate metabolomic researches between labelled IBISA platforms in Bordeaux (Metabolome : INRA, Bordeaux University), Paris (MetabolomeIDF, Paris-Saclay, CEA and Pierre and Marie Curie University), Toulouse (MetaToul, Paul Sabatier University, INSA, INRA, CNRS and INSERM), and Clermont-Ferrand (Exploration du Métabolisme, INRA and Blaise Pascal University) has been funded. The lipidomic platform in which several members of the LBM are implicated will be largely involved in the future development of new MS/MS lipid methodologies.
 

[Avril 16, 2012] Since the 1st of January 2012, ADERA (Association pour le Développement de l'Enseignement et des Recherches auprès des universités, des centres de recherche et des entreprises d'Aquitaine) created a technology transfer unit leaned back on our UMR (http://www.adera.fr/spip.php?article32). Its name: LEB Aquitaine Transfert, LEB stating for "Lipids, Environment and Biotechnologies". The main missions are to provide expertise and conduct research works in two distinct areas: 1/ Ecotoxicology (using the lipids as diagnostic tools), and 2/ Biotechnology of lipids of industrial interest.  Marina Le Guédard (Engineer-PhD) is the R&D responsible.


[March 30 , 2012]  Emmanuelle Bayer, member of the raft team at the LBM, has recently published with her former group in Bern Switzerland, headed by R. Smith and C. Kuhlemeier a paper published in Science. This work shows for the first time that mechanical signals are not just passive readouts of gene action but can feed back on morphogenesis.


[March 6-7 , 2012] Laetitia Fouillen came back from the 2nd Graz Lipid Mass Spec Meeting where she had the chance to learn and talk with lipid mass spec specialists. She presented a poster on the variability of fatty acid and TAGs compositions in palm oil using lipidomics.

[Mars 1, 2012] The LBM welcome several students : two M2 students, Camille Delude who is working with Fred Domergue in the wax team and Etienne Legrand who is working on palm oil synthesis with Vincent Arondel; two M1 students, Simon Vanderliden with Claire Bréhelin and Julien Gronnier with Jérôme Joubès.

[February 6, 2012] We welcome in the lab Guillaume Bouyssou, a new assistant engineer who will work for 2 years on the ANR project ACETOTRYP lead by Fréderic Bringaud (RMSB, Bordeaux), Jean-Charles Portais (INSA, Toulouse) and Patrick Moreau at the LBM.

[February 2, 2012] Laetitia Fouillen (left) from the LBM represented the lipidome department of the Metabolome plateform at the “journée utilisateur” of the Functional Genomic Center of Bordeaux (http://www.cgfb.u-bordeaux2.fr/). Tristan Richard (left) et Catherine Deborde (right) are other members of the Metabolome platform.





[January 9, 2011 ] The wax team decided to work on a new endemic species found in the lab. Good luck Amélie. Thanks god we are moving soon !!


[January 5, 2011 ] Yohann Boutte arrives in the lab as CR-CNRS in Patrick Moreau's team, after 6 years in Umeå, Sweeden, as postdoc in Markus Grebe and then Rishi Bhalerao labs. We wish you all the best for your installation in Bordeaux and your experiments.
                                                                                 

[December 21, 2011] The LBM is happy to congratulate our former post-doc Sylvain Raffaele, admitted CR1 INRA to work on Sclerotina / Arabdopsis at the LIPM in Toulouse with Dominique Roby and Yves Marco. Good luck for your future Sylvain. We were happy to have you two years in our lab.

[December 9, 2011]  Amélie Bernard get today her phD diploma in the wax team ! congrats.

[November 10,  2011] Rémi Zallot get today his phD diploma in the lipase team ! Congratulation

[November 22, 2011] The famous “coffee NDR1” paper finally got accepted into BMC Plant Biology upon a long-lasting review process. Congratulations to all authors… and think of it when you have a coffee break! "Identification and characterization of the Non-race specific Disease Resistance 1 (NDR1) orthologous protein in coffee". Cacas JL, Petitot AS, Bernier L, Estevan J, Conejero G, Mongrand S, Fernandez D. BMC Plant Biol, Oct 24;11:144.

[November 21, 2011] The evaluation of the toxic effects of pollutants is difficult to grasp in a real and complex environment. We recently evidenced using Lactuca serriola that plant leaf fatty acid composition measured in situ would provide an early indication of a plant’s exposure to metal and could be used as a reliable tool to facilitate or strengthen the diagnosis of soil contamination.
Le Guédard et al (2012). Env. Exp. Bot,76, 54-59.

We recently characterized a new lyso-PA acyltransferase regulating the amount of triglycerides (TG) in S. cerevisiae. Using a lipidomic approach (HPTLC-GC; MS/MS) we demonstrated that this enzyme is responsible for the incorporation of oleic acid both in phospholipids and TG, whereas quantitatively only TG were decreased in mutant cells. In addition we showed by immunoblot, proteomic and confocal studies that this enzyme is mainly located in ER membranes and in lipid droplets during the exponential and the stationary phases respectively.
Ayciriex et al. (2012) Mol Biol Cell, in press


[November 17 and 18, 2011] We are hosting Drs Martine Devic and Thomas Roscoe from the Epigenetic Regulation and Seed Development Group, IRD, Montpellier. They did experiments to determine the lipid composition changes of different mutants of Arabidopsis thaliana and presented their results.

[September, 2011] Welcome to Agnès Chevin the new administrator of the lab.

[November 2, 2011] ICON strikes again!!! Collaboration between labs from Sweden, Canada, Australia and the LBM, all partners of the large collaborative project ICON (http://icon.slu.se/ICON/index.htm), resulted in the in vitro functional characterization of the plastidial fatty acid reductase AtFAR6. Have a look at its unexpected catalytic capacities in our  "Publications" section.!!!

[October 21, 2011] Do not forget two importante dates for the lab, Rémi from the "Storage lipid metabolism" team will defend his thesis Thursday November 10th and Amélie  from the "wax" team will defend her thesis Friday December 9th.

[October 15, 2011]  After a master 2 on plasmodemata with Emmanuelle Bayer last year, Houda Nacir begins this month her thesis with Claire Brehelin on plastoglobules, granted by the Conseil Régional d'Aquitaine, FRANCE.


[October 14, 2011] Good bye Jean Luc, After 2 years at the LBM and a successful post-doc, you leave to Dijon to work on defence signalling. All the best !!!


[October 1, 2011] Sébastien Mongrand has been nominated at the section 28 "Biologie végétale intégrative" of the comité national. http://www.cnrs.fr/comitenational/sections/section28.htm

[September 27, 2011] Rene Lessire was in Rotterdam, as a member of the scientific committee of the 9th EuroFed Lipid Congress “Oil, Fats and Lipids for a Healthy and Sustainable World” with more than 600 participants,150 lectures and 250 posters. René was chairman of the “Oilseeds, Plant breeding, Plant lipids” session and he presented a lecture on Arabidopsis CER1, the function of  which has been recently elucidated by Amélie Bernard and her collegues.
More information at: http://www.eurofedlipid.org/meetings/archive/rotterdam/index.htm


[September 22, 2011] Patrick Moreau came back from The Society for Experimental Biology SEB meeting « Exocytosis in animals, fungi and plants »   organized in London by Viktor Zarsky (University of Praha), and where he gave a conference on “Links between lipid biosynthesis, organelle morphology and protein trafficking in plant secretory pathways”. This meeting gave a large part to plant research and exciting comparisons were discussed between plant cells and other eukaryotic models. This SEB symposium was also the opportunity to estimate that plant fields have reached similar levels of excellence than their mammal and yeast counterparts. The program of the symposium can be obtained at the SEB meeting site (http://www.sebiology.org/meetings/Exocytosis/index.html).



[September 12,  2011] Check our new review on Plant Rafts in Current Opinion in Plant Biology by the raft team (Sébastien, Artemis and Emmanuelle) together with our collaborators from Dijon, Françoise Simon-Plas and Patricia Gerbeau-Pissot. We discuss a working model of the putative involvement of rafts in the activation of RbohD after elicitation by PAMP.
This article is now published online at: http://dx.doi.org/10.1016/j.pbi.2011.08.003
Keep also track of lab updates publication with the "Activités" section.


[September 8, 2011] Have  a look at our last publication in PNAS, written with our swiss friends from Neuchâtel co-written by Claire Bréhélin from the LBM, about the plastoglobule localized enzyme AtNDC1 (a type II NADPH quinone oxidoreductase) and its role in plastoquinone oxidoreduction and prenylquinone metabolism. http://www.pnas.org/content/108/34/14354.long
Beside, all you always dreamt to know about Arabidopsis plastoglobule preparation is explained by Claire and her colleagues in this new chapter of Methods in Molecular Biology.
Besagni et al., " Preparation of Plastoglobules from Arabidopsis Plastids for Proteomic Analysis and Other Studies" http://www.springerlink.com/content/r4l7803j80802744/#section=947110&page=1


[August 7, 2011] Viva Argentina !!! Owing to the ECOS-SUD France-Argentina project, Sébastien spent two weeks and Artemis four weeks at the University of Buenos Aires (top left picture). Our collaborator Alicia Zelada welcomed us to work on PVX propagation and the involvement of the plant raft protein REMORIN (bottom left picture, from left to right: Maria BINAGHI, Sébastien MONGRAND, Alicia ZELADA and Artemis PERRAKI).
We took the opportunity to visit Iguaçu Falls and the city of Buenos Aires and its strange baobabs…


[July 18, 2011] We're back from Gdansk in Poland where the 5th european Symposium on Plant Lipids took place. As always, the congress was very interesting, we met lot of colleagues and several people from the lab had the opportunities to present their work (Amélie, Vincent, Fred, Rémi and Jérôme).



[June 27, 2011] Jean-Jacques Bessoule et Marina Le-Guedard came back from the island of Skiathos in Greece. Lucky you ! They attended the Third International CEMPE (Conference on Environmental Management , Engineering, Planning and Economics)  and SECOTOX (Society of Ecotoxicology and Environmental Safety and its Regional Sections) conferences.  An utmost interested congress dedicated to environment and ecotoxicology.


[June 28, 2011] Our Laboratory (Oil group led by V. Arondel), in collaboration with John Ohlrogge's laboratory (MSU, USA) and two African scientists, has given a major contribution to a carbon partitioning study in palm mesocarps, which is now out in PNAS. Aside from its fundamental interest, this work opens the way to genetic improvement of oil palm, a major crop that grows almost exclusively in developing countries, with probable important long-term impact on development of these countries' agriculture.
Bourgis et al., 2011
[see also the CNRS press communication on the web: http://www2.cnrs.fr/presse/communique/2236.htm]
[see also:  http://www.techno-science.net/?onglet=news&news=9396]


[June 9, 2011] The research led by J. Malek in Qatar and involving worldwide collaborations including our lab (oil team led by Vincent Arondel) on the draft genome of date palm makes the cover of Nature Biotechnology. This work has important implications for improvement of the crop with impact on sustainable agriculture in developing countries.


[May 30th, 2011] The new review written by Denis Coulon and his colleagues from the "Biogenèse et Homéostasie membranaire" team on N-acylphosphatidylethanolamines NAPE, not just precursors of  N-acylethanolamines (NAE) is out in Biochimie. Have a look !

[May 27th, 2011] Owen Rowland who is associate professor at Carleton University in Ottawa is coming from Canada for 2 weeks. He is supported by a France Canada Research Fund (FCRF) that he obtained in collaboration with Frédéric Domergue.

[May 17th, 2011] The collaborative paper of the two Patricks : Patrick Moreau from LBM and Patrick Legembre from University of Rennes, IRSET (Institut de Recherche en Santé, Environnement et Travail) about the  the oncogenic PI3K/Akt signalling pathway is out in European journal of Immunology
Pizon et al., PI3K/AKT inhibition elicits actin-independent and CD-95-dependent apoptic signalling through localisation of CD95 into lipid rafts.


[May 5th, 2011] We are hosting Reinhard Jetter who is  professor at the University of British Columbia in Canada for one month in the lab. He is supported by a France Canada Research Fund (FCRF) that he obtained in collaboration with the people of the wax team.

[April 8th, 2011] The BSM paper of our belgium colleagues is out on line. The additional news are that PNAS Editorial Board selected our suggestion image for the cover of the print issue on the 19th April.
Babiychuk et al., Plastid gene expression and plant development require a plastidic protein of the mitochondrial transcription termination factor family.


[March 30th, 2011], the lab thanks Stéphane Blanc from INRA, Montpellier, and Christiane Laurière from ISV/CNRS, Paris for their participation of the mid-term PhD comitee of Artemis Perraki.

[March 30th, 2011] We are hosting Dr Christiane Lauriere from the Institute of Plant Sciences , Gif-sur-Yvette. She will talk about "Mechanisms of regulation of the SnRK2 kinase in osmotic signalling".

[March, 25th 2011]. Coming for the Rehearsal of the CNRS competition, we listen to Yohann Boutté' post-doc stories in Umeå Plant Science Centre, Sweeden, on phytosterols and sphingolipids and the establisment of cell polarity. Good luck Yohann for the competition !

[March 21st, 2011] We are hosting Maria Binaghi from the University of Buenos Aeres, Argentina, for three months in the lab. She is supported by a short EMBO fellowship and will work on REMORIN and PVX virus propagation. Good luck for the experiments and enjoy Bordeaux.


[March 15th, 2011] Eric Maréchal, Laboratoire de Physiologie Cellulaire Végétale, CEA, Grenoble, France, stopped by the lab and presented a talk on the chemical inhibition of galactolipid synthesis by molecules competing diacylglycerol.